Protein Interaction Antibody Pairs
ABclonal Technology CDK4 Rabbit pAb
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
Sino Biological Recombinant Human C5AR1/C5R1/CD88 Protein (VLP, Full-Length, Flag Tag)
A DNA sequence encoding the Human C5AR1 (P21730) (Met1-Val350) was expressed with a flag tag at the N-terminus.
Meso Scale Discovery RPLEX HUM BclX/Bcl2L1 ASYQP
The R-PLEX Human Bcl-xL/Bcl2-L-1 Assay Kit from Meso Scale Discovery measures Bcl-xL and Bcl2-L-1 protein levels in human samples like serum plasma and cell lysates This electrochemiluminescent immunoassay uses MSD s SULFO-TAG labels and multi-array plate technology for sensitive detection The kit includes a 96-well plate with capture antibodies detection antibodies with ruthenium labels calibrators and necessary reagents Results analyzed on MSD systems offer insights into apoptotic regulation pathways with high sensitivity and minimal sample needs
Cusabio Technology LLC Recombinant Human Claudin-3 CLDN3 VLPs active20ug
Recombinant Human Claudin-3 CLDN3 VLPs active20ug
ABclonal Technology NCK1 Rabbit mAb
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
ABclonal Technology FasLG Rabbit pAb
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.